The bipolar disorder is also known as a manic-depressive illness and manifests in the form of extreme shifts in mood ranging from a manic to a depressive state. It is a brain disorder which causes unusual shifts in energy, mental status, mood, activity levels, etc.


  1. feeling sad, hopeless or irritable most of the time
  2. lacking energy or feeling full of energy
  3. difficulty concentrating and remembering things
  4. loss of interest in everyday activities
  5. feelings of emptiness/worthlessness or feeling self-important
  6. feelings of guilt and despair
  7. feeling pessimistic about everything
  8. self-doubt
  9. being delusional
  10. having hallucinations
  11. disturbed or illogical thinking
  12. lack of appetite
  13. difficulty sleeping
  14. waking up early
  15. suicidal thoughts
  16. feeling very happy
  17. talking very quickly
  18. feeling full of great new ideas
  19. Having important plans
  20. being easily distracted
  21. being easily irritated or agitated
  22. being delusional, having hallucinations and disturbed or illogical thinking
  23. not feeling like sleeping
  24. not eating
  25. doing things that often have disastrous consequences – such as spending large sums of money on expensive and sometimes unaffordable items
  26. making decisions or saying things that are out of character and that others see as being risky or harmful

Risk Factors

  • Family history
  • StressFamily history
  • Stress

Diagnostic Tests

  • Psychiaatric assessment
  • Magnetic Resonance Imaging
  • Electrocardiography
  • Electroencephalography
  • Blood Tests

Differential Diagnosis

  • Anxiety Disorders
  • Head Trauma
  • Hyperthyroidism
  • Hypothyroidism
  • Iatrogenic Cushing Syndrome
  • Lyme Disease
  • Multiple Sclerosis
  • Neurosyphilis
  • Pediatric Attention Deficit Hyperactivity Disorder (ADHD)
  • Physical Medicine and Rehabilitation for Systemic Lupus Erythematosus
  • Posttraumatic Stress Disorder
  • Schizoaffective Disorder
  • Schizophrenia
  • Seasonal Affective Disorder


  • Drugs (Antipsychotics, Antidepressants & Anticonvulsants)
  • Psychiatric treatment
  • Electroconvulsive Therapy


  • Valproate
  • Carbamazepine extended release
  • Lamotrigine
  • Lithium
  • Aripiprazole
  • Ziprasidone
  • Risperidone
  • Asenapine
  • Quetiapine
  • Chlorpromazine
  • Cariprazine
  • Olanzapine
  • Olanzapine/fluoxetine combination

Lifestyle Management

  • Regular exercise
  • Better Diet
  • Good night sleep