WALDENSTROM MACROGLOBULINEMIA

Description

It is associated with the overproduction of proteins called IgM antibodies

Symptoms

  • Weakness
  • Fatigue
  • Bleeding from the gums or nose
  • Weight loss
  • Bruises
  • Skin lesions
  • Skin discoloration
  • Swollen glands
  • Skin itchiness
  • Vision changes
  • Headache
  • Dizziness or vertigo
  • Change in mental status

Causes

  • Hyperviscosity
  • Hereditary

Diagnostic Tests

  • Physical examination
  • Blood tests
  • Biopsy
  • Bone marrow aspiration
  • CT scan
  • MRI
  • Positron emission tomography (PET)
  • Fundascopic evaluation
  • Urine Test

Treatment

  • Plasma exchange
  • Chemotherapy
  • Targeted therapy
  • Stem cell transplantation/bone marrow transplantation
  • Biotherapy
  • Medicine :
  • Rituximab

Lifestyle Management

  • Manage emotions
  • Provide support and encouragement
  • Take medicines