Virinchi Hospitals – Best Hereditary Kidney Disease Treatment Hospital in Hyderabad

Due to mutations in one or many genes almost sixty various types of kidney diseases with varying degrees of onsets, incidence and severities can cause local to systemic health conditions including renal cancers.

  • Alport Syndrome
  • Aminoacidurias
  • Autosomal dominant polycystic kidney disease
  • Autosomal recessive distal RTA with deafness
  • Autosomal recessive polycystic kidney disease
  • Bardet-Biedl syndrome
  • Bartter syndrome, Types 1–4
  • Branchio-oto-renal syndrome
  • Cystinosis
  • Dent’s disease, Type 1
  • Diabetes insipidus, nephrogenic
  • Distal renal tubular acidosis type I
  • Fabry disease
  • Focal Segmental Glomerulosclerosis
  • Gitelman syndrome
  • Glucose-6-phosphatase deficiency / Glycogen storage disease type I (GSDI)
  • Gordon syndrome / Pseudohypoaldosteronism type II, PHA-II
  • Hemolytic uremic syndrome, atypical
  • Hypomagnesemia
  • Hypophosphatemic
  • Idiopathic Nephrotic Syndrome
  • Kidney hypoplasia
  • Liddle syndrome
  • Lowe syndrome
  • Meckel-Gruber syndrome
  • Medullary cystic kidney disease
  • Mitochondrial cytopathy, Maternally Inherited Diabetes and Deafness (MIDD-type)
  • Nephronophthisis
  • Osteoonychodysplasia
  • Papillary renal cell carcinoma
  • Primary hyperoxaluria
  • Proximal renal tubular acidosis
  • Proximal renal tubular acidosis (RTA)
  • Pseudohypoaldosteronism type 1
  • Renal coloboma syndrome
  • Renal dysplasia
  • Renal glucosuria
  • SeSAME syndrome
  • Thin Basement Membrane Nephropathy
  • Tuberous Sclerosis
  • Von-Hippel Lindau Syndrome
  • Wilms-tumor-aniridia syndrome

Owing to their occurrence due to inheritance, most of the inherited renal diseases are identified at an early stage during childhood. The inherited kidney diseases may also occur along with other conditions such as liver diseases, intellectual disability, seizures, tumours and skin lesions with following symptoms & complications

Hereditary Kidney Disease Symptoms

  • Mental retardation
  • Drooping of eye lids
  • Dry skin
  • Short stature
  • Vision problems
  • Absence of nails & knee caps
  • Dementia
  • Heightened emotions
  • Progressive deafness
  • Muscle weakness
  • Chest Pain
  • Low urine output

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Hereditary Kidney Disease Complications

  • Rickets
  • Acidosis
  • Hypertension
  • Diabetes insipidus
  • Diabetes Mellitus
  • Anaemia
  • Myopathy
  • Gout
  • Solitary Kidney
  • Problems with urinary excretion Portal hypertension
  • Portal hypertension
  • Ventricular hypertrophy
  • Arrhythmias
  • Acromegaly
  • Angiokeratoma
  • Cardiomyopathy
  • Valvular disease
  • Septal defects
  • Splenomegaly and Hepatomegaly
  • Encephalopathy
  • Pigmentary retinopathy
  • Stroke
  • Ataxia
  • Delayed puberty
  • Renal parapyelic cysts
  • Proteinuria
  • Renal Failure
  • Polyuria
  • Fanconi syndrome
  • Focal segmental glomerular sclerosis
  • Tubulo-interstitial nephritis
  • Nephrocalcinosis
  • Hypercalciuria
  • Fanconi syndrome
  • Microscopic hematuria
  • Angiomyolipomas
  • Renal cysts
  • Oligomeganephronia
  • Renal hypoplasia
  • Vesicoureteral reflux
  • Interstitial nephritis

Our nephrologists work in collaboration with a team of multidisciplinary experts including geneticists, cardiologists, surgeons, pathologists and radiologists to evaluate and manage the all the conditions suitably.

Diagnosis of Hereditary Kidney Diseases

With the help of genetic testing, computed tomography magnetic resonance or ultrasound guided imaging and also renal biopsies provide details on of the molecular and anatomical abnormalities and help our experts devise patient specific treatment plans for effective outcomes. We also offer screening services for individuals with a family history of inherited kidney diseases.

Treatment of Hereditary Kidney Diseases

Since there is no gene therapy available to date, medical management of the inherited conditions are in practice with medication, surgeries, biological therapies, dietary modifications and renal transplantation. Genetic counselling can help in avoiding spread of the conditions by avoiding marriages between relatives of known family history. In case of polycystic kidney disease treatment, two consecutive of surgeries are performed; one to remove the diseased kidney and the other one to transplant a healthy donor kidney. Our transplant surgeons are experts in performing such kind of procedures successfully through minimally invasive means with minimum scars and quicker postoperative recovery.


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