X-LINKED AGAMMAGLOBULINEMIA

Description

Inherited immunodeficiency in which the body is unable to produce antibodies needed to defend against bacteria and viruses

Symptoms

  • Ear and skin infections
  • Sinusitis
  • Pneumonia
  • Diarrhea
  • Sepsis
  • Osteomyelitis
  • Meningitis
  • Bronchitis
  • Autoimmune hemolytic anemia
  • Joint disease
  • Growth failure

Causes

  • Mutation on X chromosome

Risk Factors

  • Affects mostly males

Diagnostic Tests

  • physical examination
  • Screening test
  • Blood tests

Treatment

  • Antibody replacement
  • Oral antibiotics
  • Prompt treatment of infections

Prevention

  • Early diagnosis
  • Avoid live viral vaccines