WERNICKE-KORSAKOFF SYNDROME

Description

It is a brain disorder due to vitamin B1 (thiamine) deficiency

Symptoms

  • Double vision
  • Dropping upper eyelid
  • Up-and-down or side-to-side eye movements
  • Loss of muscle coordination
  • Confused mental state
  • Amnesia
  • Difficulty understanding the meaning of information
  • Difficulty putting words into context
  • Hallucinations
  • Confabulation

Causes

  • Alcoholism
  • Limited nutritional absorption
  • Lack of vitamin B1

Risk Factors

  • Malnourishment
  • Chronic alcoholism
  • Kidney dialysis
  • AIDS

Diagnostic Tests

  • Neuropsychological test
  • Liver function test
  • Electrocardiogram (EKG)
  • CT scan
  • MRI
  • Nutritional tests :
  • Serum albumin test
  • Serum vitamin B-1 test

Treatment

  • Vitamin B-1 through IV or oral
  • Balanced diet
  • Abstinence from alcohol
  • Thiamine supplements

Lifestyle Management

  • Alcohol recovery program
  • Rehabilitation
  • Regular dose of thiamine supplements,vitamins and electrolytes