• a disease that causes the loss of skin color in blotches.
  • can affect the skin on any part of your body


  1. In a focal pattern, the loss of skin color appears in only a few small areas.
  2. In a segmental pattern, depigmentation occurs on one side of the body.
  3. In a generalized pattern, the loss of melanin occurs on both sides of the body in a symmetrical pattern.
  4. Skin discoloration
  5. Premature whitening or graying of the hair on your scalp, eyelashes, eyebrows or beard (usually before age 35)
  6. Loss of color in the tissues that line the inside of your mouth and nose (mucous membranes)
  7. Loss of or change in color of the inner layer of the eyeball (retina)
  8. Discolored patches around the armpits, navel, genitals and rectum


  1. A disorder in which your immune system attacks and destroys the melanocytes in the skin
  2. Family history (heredity)
  3. A trigger event, such as sunburn, stress or exposure to industrial chemicals
  4. neuro chemicals

Risk factors

  • a family history of other autoimmune conditions
  • another autoimmune condition
  • melanoma,lymphoma
  • changes in your genes that are known to be linked to non-segmental vitiligo
  • stressful events – such as childbirth
  • damage to your skin – such as severe sunburn or cuts (this is known as the Koebner response)
  • exposure to certain chemicals

Diagnostic Tests

  • medical examine
  • biopsy of skin
  • blood test


  • Skin camouflage
  • protection from sun
  • vitamin D
  • topical corticosteroids
  • Phototherapy
  • skin grafts
  • depigmentation
  • immunomodulators
  • surgery
  • laser therapy
  • blister grafting


  • Topical calcipotriene (Dovonex)
  • tacrolimus or pimecrolimus (calcineurin inhibitors)

Lifestyle Management

  • referral to a support group
  • Protect your skin from the sun and artificial sources of UV light
  • Conceal affected skin
  • don’t get a tattoo