1. condition where blood flow to your fingers, toes, ears, or nose is restricted or interrupted
  2. smaller arteries that supply blood to your skin narrow, limiting blood circulation to affected areas (vasospasm)


  1. Cold fingers or toes
  2. Color changes in your skin in response to cold or stress
  3. Numb, prickly feeling or stinging pain upon warming or stress relief


  1. smoking
  2. use of medications and drugs that narrow your arteries, such as beta-blockers and amphetamines
  3. arthritis
  4. atherosclerosis, which is hardening of your arteries
  5. autoimmune conditions, such as lupus, scleroderma, rheumatoid arthritis, or Sjogren’s disease
  6. cold temperatures
  7. emotional stress
  8. working with hand tools that emit vibrations
  9. Carpal tunnel syndrome.
  10. smoking
  11. injuries

Risk Factors

  • Associated diseases. 
  • age
  • climate
  • family history
  • Exposure to certain substances
  • Certain occupations.

Diagnostic Tests

  • antinuclear antibodies (ANA) test 
  • erythrocyte sedimentation rate
  • a full blood count


  • beta-blockers
  • estrogen-based drugs
  • migraine medicines
  • birth control pills
  • pseudoephedrine-based cold medicines
  • antidepressants
  • antihypertension medications
  • erectile dysfunction drugs
  • calcium channel blockers,vasodilators


  •  nifedipine (Afeditab CR, Procardia), amlodipine (Norvasc) 
  • felodipine (Plendil)
  • prazosin (Minipress) and doxazosin (Cardura).
  • losartan (Cozaar)
  • sildenafil (Viagra, Revatio)
  •  fluoxetine (Prozac, Sarafem, others)
  • pseudoephedrine (Chlor-Trimeton, Sudafed, others)
  • metoprolol (Lopressor, Toprol-XL), nadolol (Corgard),propranolol (Inderal, InnoPran XL).
  • anesthetics or onabotulinumtoxin type A (Botox)

Lifestyle Management

  • Keep your whole body warm, especially your hands and feet
  • avoid smoking
  • reduce stress
  • exercise
  • healthy diet