Pick’s disease is a rare form of dementia that is similar to Alzheimer disease, except that it tends to affect only certain areas of the brain


  • Behavioral and emotional symptoms,
  • abrupt mood changes
  • compulsive or inappropriate behavior
  • depression
  • withdrawal from social interaction
  • difficulty keeping a job
  • poor social skills
  • poor personal hygiene
  • repetitive behavior
  • language and neurological changes
  • reduced writing or reading skills
  • echoing, or repeating what’s been said to you
  • inability to speak, difficulty speaking, or trouble understanding speech
  • shrinking vocabulary
  • accelerated memory loss
  • physical weakness


  • Cause by abnormal amounts of nerve cell proteins called tau
  • different abnormal genes

Diagnostic Tests

  • Neuro psychological assessment
  • Brain MRI
  • Electroencephalogram (EEG)
  • Examination of the brain and nervous system (neurological exam)
  • Examination of the fluid around the central nervous system (cerebrospinal fluid)
  • Head CT scan
  • Cognitive function and motor function tests
  • brain biopsy


  • No specific treatment for Pick disease
  • Medicines to reduce symptoms include:
  • Analgesics
  • Anticholinergics
  • Central nervous system depressants
  • Cimetidine
  • Lidocaine