PHEOCHROMOCYTOMA

 

Description

A   pheochromocytoma  is a rare, usually noncancerous (benign) tumor that develops in cells in the center of an adrenal gland.

Symptoms

  • Common signs and symptoms
  • High blood pressure
  • Rapid or forceful heartbeat
  • Profound sweating
  • Severe headache
  • Tremors
  • Paleness in the face
  • Shortness of breath
  • Less common signs or symptoms
  • Anxiety or sense of doom
  • Abdominal pain
  • Constipation
  • Weight loss

Cause

  • Role of hormones
  • related tumors

Risk factors

  • Multiple endocrine neoplasia, type II
  • Von Hippel-Lindau disease
  • Neurofibromatosis 1 (NF1)
  • Hereditary paraganglioma syndromes

Diagnostic Tests

  • Laboratory tests
  • 24-hour urine test
  • Blood test
  • Imaging tests
  • CT scan
  • MRI
  • PET
  • M-iodobenzylguanidine (MIBG)
  • Incidental discovery
  • Genetic testing

Treatment

  • Beta blockers, which inhibit the effect of adrenaline
  • Other medications
  • Surgery
  • Cancer treatments
  • Radionuclide treatment
  • Chemotherapy
  • Targeted cancer therapies.