GRANULOMATOSIS WITH POLYANGIITIS

Description

It is a rare disease that causes inflammation of the blood vessels in nose, sinuses, throat, lungs and kidneys

Symptoms

  • Runny nose, stuffiness and nosebleeds
  • Rinus infections
  • Shortness of breath
  • Fever
  • Fatigue
  • Numbness in your limbs, fingers or toes
  • Weight loss
  • Hematuria
  • Skin sores or bruising
  • Eye redness, burning or pain
  • Ear infections
  • Joint pains

Causes

  • Infection with bacteria or virus
  • Granulomas

Risk Factors

  • Affects people between the ages of 40 and 65

Diagnostic Tests

  • Blood test
  • Urine tests
  • Biopsy
  • CT scan
  • MRI scan

Treatment

  • Intravenous immunoglobulin therapy (IVIG)
  • Corticosteroids to control inflammation
  • Plasma exchange
  • Kidney transplant
  • Inducing remission
  • Medicines :
  • prednisone
  • Cyclophosphamide (Cytoxan)
  • Azathioprine Imuran)
  • Methotrexate (Rheumatrex, Trexall)
  • Rituximab (Rituxan)

Prevention

  • Early diagnosis
  • Maintaining remission

Lifestyle Management

  • Understand the condition
  • Maintain a strong support system